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The science

Christoph and James discussing samples in the lab.

How do we fight gout? 

 Excessive uric acid levels are the root cause of gout, a excruciatingly painful form of arthritis. Uric acid is a normal waste product of healthy human metabolism. If uric acid levels get too high, needle-sharp uric acid crystals can start to form inside joints throughout the body. The resulting inflammation is extremely painful and can cause permanent joint damage.

 At unlocked labs, we are developing a patent-pending probiotic that is programmed to biodegrade uric acid in the gut. By eliminating uric acid in the GI tract, we turn the gut into a 'net sink' capable of lowering levels throughout the body.

 There are many over-the-counter supplements that are marketed towards gout. None of these are backed with scientific evidence.


 At unlocked labs, we are working to develop an effective, safe, and affordable gout solution. The active ingredient (probiotic microbes) stay in the gut and doesn’t enter the bloodstream - unlike prescription drugs. Because microbes stay out of the circulation, they are safe for liver and kidneys.

Go with your gut! 

 Our microbes are based on a probiotic bacterium that has been studied for decades, and is completely safe for human consumption. This bacterium is called Bacillus subtilis. It has the natural ability to take up uric acid and break it down into a harmless waste product. We programmed this probiotic strain using modern synthetic biology to enhance this natural therapeutic potential. We're turning its power into a superpower!   

 Biodegrading metabolic waste products like uric acid in the intestine turns the gut into a net sink. Because the rest of the body balances with the intestine, this reduces uric acid levels throughout the body. Unlike other supplements, our products are designed to target the root causes of chronic conditions.

 Our goal is to let you decide for yourself: we will provide you with peer-reviewed scientific studies to show our products are safe and effective. unlocked labs' microbes will be available over-the-counter, and you won't need to see a doctor to get a prescription for our supplements.

James and Christoph analyizing samples in a lab using a microscope.
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